The Lexia in Rome program is affiliated with the Istituto Italiano, a university-level institution specializing in the instruction of Italian language and culture to foreigners. Lexia students have access to the libraries of the British Consul, the National Library of Italy, the Santa Suzanna American Library and the Lexia program library. Facilities and instruction for students in music, studio art, restoration or other fields can be arranged. Students can also attend lectures at the American Academy in Rome and national academies and the numerous educational institutions in Rome in addition to the program lectures. The Istituto Italiano makes its extensive collection of classic and contemporary Italian films available on video and DVD.

One of the recognized strengths of the Lexia program in Rome is the strong supporting faculty and staff who can tailor and adapt special studies to individual student needs. Courses are taught by the Resident Director, Italian professors, and other professionals. Speakers are also drawn from industry and the government sector.